CORONAVIRUS (COVID-19) RESOURCE CENTER Read More

Add To Favorites

Ver en español

Indirect Coombs Test

Overview

An indirect Coombs test can be used to determine whether there are antibodies to the Rh factor in the mother's blood. In this case:

  • A normal (negative) result means that the mother has not developed antibodies against the fetus's blood. A negative Coombs test indicates that the fetus is not presently in danger from problems relating to Rh incompatibility.
  • An abnormal (positive) result means that the mother has developed antibodies to the fetal red blood cells and is sensitized. However, a positive Coombs test only indicates that an Rh-positive fetus has a possibility of being harmed. A positive test cannot indicate the amount of fetal harm that has occurred or is likely to occur.

If test results show that antibody amounts are increasing during pregnancy, the fetus may be at greater risk of harm.

A fetus who is Rh-negative will not be harmed, even if the mother is sensitized.

Credits

Current as of: May 13, 2023

Author: Healthwise Staff
Clinical Review Board
All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

© 1995-2024 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.